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Natural Highs Salvia Tincture Carl Epling, who first described S. divinorum, reported the newer as having a blue corolla, and it has been illustrated this way in the literature (Epling and Jativa-M, 1962; Schultes, 1976). However, this description Smoking Salvia Guaranitica has been shown to be an error, as all living specimens of New Highs the plant have had blossoms with white corollas and purple calyces (Diaz, 1975a; Emboden, 1979). Carl Epling, who first described S. divinorum, reported the newer as having a blue corolla, and it has been illustrated this way in the literature (Epling and Jativa-M, 1962; Schultes, 1976). However, this description has been shown to be an error, as all living specimens of the plant have had blossoms with white corollas and purple calyces (Diaz, 1975a; Emboden, 1979). Salvia divinorum (also known as Diviner's sage, María Pastora or simply Salvia, although the genus name is salvia guaranitica effects shared among many plants) is a psychoactive plant, a member of the sage genus and the Lamiaceae (mint) family. The plant is grown by the Mazatec indigenous people of the Oaxaca mountains of southern Mexico in isolated, moist, and secret plots. It has been used as an entheogen by their shamans Hallucinogen Music Saliva for centuries for healing during spirit journeys. It is thought what is salvia Salvia Diviorum Supplier Chicago Salvia Divonorum to be a cultigen. No definitively wild populations have been found. The Latin name Salvia divinorum literally translates to Salvia Div "sage of the diviners". The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. R. Gordon Wasson, the famed ethnobotanist who introduced psilocybe mushrooms to western society, was also the first to personally describe an experience with Salvia divinorum. In July of 1961 he participated in a healing ceremony performed by a Mazatecan curandera. Wasson ingested the squeezed juice of 34 pairs of leaves, and described the results as "coming on sooner (than the mushrooms), being less sweeping, and lasting a shorter time. It did not go beyond the initial effects of the mushrooms - dancing colors in elaborate, three- dimensional designs." In 1962 Wasson was joined in Oaxaca by Swiss pharmacologist Albert Hofmann, inventor of LSD, who also first isolated psilocybin from mushrooms gathered in this same region. Hofmann brought Saliva Rest In Pieces Lyrics an alcohol extract of Salvia divinorum back to Switzerland where he attempted to isolate the active component. He was unsuccessful, finding the extract to no longer be active, and suggested that the plant's active principal was unstable. But who knows? Maybe she was wearing her own pheromone formula, which has been proven to attract the opposite sex, at least according to the "double-blind, placebo-controlled scientific study" continually mentioned on the Athena Pheromone 10X site The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action.
Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation. Unless you believe that Salvia divinorum is the old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint DAMIANA Contact DAMIANA began in the late 1930s. When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for decades (Pompa y Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary. The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as Salvinorin Sagewisdom 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated EFFECTS EFFECTS EFFECTS that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action.The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1. Recent research has shown that salvinorin A Goatrance is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action.The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and the psilocybin-containing mushrooms. " Even though it may sound like it from that sentence, we should not assume that Dr Unless you believe that Salvia divinorum is the old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint began in the late 1930s. When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for decades (Pompa y Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary. " Even though it may sound like it from that sentence, we should not assume that Dr Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and the psilocybin-containing mushrooms. R. Gordon Wasson, the famed ethnobotanist who introduced psilocybe mushrooms to western society, was also the first to personally describe an experience with Salvia divinorum. In July of 1961 he participated in a healing ceremony performed by a Mazatecan curandera. Wasson ingested the squeezed juice of 34 pairs of leaves, and described the results as "coming on sooner (than the mushrooms), being less sweeping, and lasting a shorter time. It did not go beyond Zaubersalbei About Zaubersalbei the initial effects of the mushrooms - dancing colors in elaborate, three- dimensional designs." In 1962 Wasson was joined in Oaxaca by Swiss pharmacologist Albert Salvio Salvorin Hofmann, inventor of LSD, who also first isolated psilocybin from mushrooms gathered in this same region. Hofmann brought an alcohol extract of Salvia divinorum back to Switzerland where he attempted to isolate the active component. He was unsuccessful, finding the extract to no longer be active, and suggested that the plant's active principal was unstable. Unless you believe that Salvia divinorum is the old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint began in the late "Caroline Salvia" 1930s. Dorium Plant Plant Salvi Dorium When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling Salvia Divinorum Rare Plant Found In Mexican Mountains to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca Yrtit under the Salvia Hotel auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for decades (Pompa y Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary.
The law: Not controlled under the Misuse of Drugs Act Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during Caroline Salvia Excess Saliva the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation. Salvia Divinorum Tincture If you are looking for that extra Madrensis something to enhance sexual performace and X Superba May Night salvia blue sexual arousal then we have a fantastic range of legal aphrodisiacs for you and your partner
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Salvia divinorum (also known as Diviner's sage, María Pastora or simply Salvia, although the genus name is shared among many plants) is a psychoactive plant, a member of the sage genus and the Lamiaceae (mint) family. The plant is grown by the Mazatec indigenous people of the Oaxaca mountains of southern Mexico in isolated, moist, and secret plots. It has been used as an entheogen by their shamans for centuries for healing during spirit journeys. It is thought to be a cultigen. No definitively wild populations have been found. The Latin name Salvia divinorum literally translates to "sage of the diviners". Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation. Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation.
The law: Not controlled under the Misuse of Drugs Act The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely Saliva Your Disease Smoke Salvia related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at Salvorin doses as low as 100 µg [1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action.The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and the psilocybin-containing mushrooms. Unless you believe that Salvia divinorum is the old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint Salvia Sclarea began in the late 1930s. When R. Gordon Wasson and Albert Hoffman Salvia Sclarea brought back material for Carl Epling to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for decades (Pompa y Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary. " Even though it may sound like it from that sentence, we should not assume that Dr R. Gordon Wasson, the famed ethnobotanist who introduced psilocybe mushrooms to western society, was also the first to personally describe an experience with Salvia divinorum. In July of 1961 he participated in a healing ceremony performed by a Mazatecan curandera. Wasson ingested the squeezed juice of 34 pairs of leaves, and described the results Salvia Plant In In Mexican Found Salvia Plant as "coming on sooner (than the mushrooms), being less sweeping, and lasting a shorter time. It did not go beyond the initial effects of the mushrooms - dancing colors in elaborate, three- dimensional designs." In 1962 Wasson was joined in Oaxaca by Swiss pharmacologist Albert Hofmann, inventor of LSD, who also first isolated psilocybin from mushrooms gathered in this same region. Salvia Seeds Hofmann brought an alcohol extract of Salvia divinorum back to Switzerland where he attempted to isolate the active component. He was unsuccessful, finding the extract to no longer be active, and suggested that the plant's active principal was unstable. Unless you believe that Salvia divinorum is the old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint began in the late 1930s. When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for decades (Pompa y Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary. R. Supplier Salvia Purple Salvia Supplier Com Gordon Wasson, the famed ethnobotanist who introduced psilocybe mushrooms salvia legal to western society, was also the first to personally describe an experience with Salvia divinorum. In July of 1961 he participated in a healing ceremony performed by salvia greggi a Mazatecan curandera. Wasson ingested the squeezed juice of 34 pairs of leaves, and described the results as "coming on sooner (than the mushrooms), being less sweeping, and lasting a shorter time. It did not go beyond the initial effects of the mushrooms - Saliva Superstar Enzo Salvi dancing colors in elaborate, three- dimensional designs." In 1962 Wasson was joined in Oaxaca by Swiss pharmacologist Albert Hofmann, inventor of LSD, who also first isolated psilocybin from mushrooms gathered in this same region. Hofmann brought an alcohol extract of Salvia divinorum back to Switzerland where he attempted to isolate the active component. He was unsuccessful, finding the extract to no longer salvia greggi be active, and suggested that the plant's active principal was unstable. Amongst the Mazatecs, Salvia divinorum (Diviner's sage) is known under such names as ska Maria Emerald Emerald Goddess Emerald Goddess Pastora and Hierba Maria, which translate as "the herb where to buy salvia of Mary" or "leaves of Mary the Shepherdess". In a recent paper, Jonathan 0tt has noted that the Mazatecs lack an indigenous name for Salvia divinorum, both the Christian theme of Mary, as well as sheep, having been introduced to the region during the Spanish conquest. The Mazatecs also list a method of consuming this plant that does not efficiently utilize its psychoactive content, and seem to be generally unaware of its tremendous potency. Based on this information, and the likelihood of its being a cultigen, Ott has suggested that Salvia divinorum may be a post-conquest introduction to the Sierra Mazateca. However, it has also been suggested, where to buy salvia initially by R. Gordon Wasson, that Salvia Trip Salvia Salvia Salvia divinorum where to buy salvia may be the Aztec plant Pipiltzintzintli, an entheogen that was briefly described by a 17th century Spanish friar. Ott has found that the little information available regarding Pipiltzintzintli supports this hypothesis, while ruling out several other plants that have been suggested as candidates for this where to buy salvia Aztec sacrament. A discussion of the role of ska Maria Pastora in the native pharmacopeia is based on previous reports and fieldwork by the authors, with a Mazatec shaman.
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Aphrodisiacs, love potions, sex enhancers, and herbal viagras Unless you believe that Salvia divinorum is the Lyrata Vinorum old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint began in the late 1930s. When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling to identify (Wasson salvia guaranitica 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to smoking salvia farinacea Oaxaca for decades (Pompa Lyrata Vinorum y Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary. If you are looking for that extra something to enhance sexual performace and sexual arousal then we have a fantastic range Diterpen Microphylla of legal aphrodisiacs for you Salvia Miltiorrhiza and your partner A discussion of the role of where can i buy Salvia divinorum clones in canada ska Maria Pastora in the native pharmacopeia is based on previous reports and Salvia Diviorum Supplier Chicago Salvia Divonorum fieldwork by the authors, with a Palatable Mazatec where can i buy Salvia divinorum clones in canada shaman. Carl Epling, who first described salvia divanorum S. divinorum, reported the newer as having a blue corolla, and it has been illustrated this way in the literature (Epling and Jativa-M, 1962; Schultes, 1976). However, this description has been shown to be an error, as all Cat Saliva Salvia Nemorosa Extract Mazatec living specimens of the plant have had blossoms with white corollas and purple Order Salvia calyces (Diaz, 1975a; Emboden, 1979). Salvia divinorum (also known as Diviner's sage, María Pastora or simply Salvia, although the genus name is shared among many plants) is a psychoactive plant, a member of the sage genus and the Lamiaceae (mint) family. The plant is grown by the Mazatec indigenous people of the Oaxaca mountains of southern Mexico in isolated, moist, and secret plots. It has been used as an entheogen by their shamans for centuries for healing during spirit journeys. It is thought to be a cultigen. No definitively wild populations have been found. Salvia Tea The Latin name Salvia divinorum literally translates to "sage of the diviners". If you are looking for that extra something to enhance sexual performace and sexual arousal then we have a fantastic range of legal aphrodisiacs for you and your partner Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and the psilocybin-containing mushrooms. Unless you believe that Salvia divinorum is the old Bouncing Bear Botanicals Divinarum Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story of this fascinating mint began in the late 1930s. When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Salvia divinorum Rare plant found in Mexican mountains Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for decades (Pompa y Salvi Harps Pompa 1966). I’ve quoted everything relative to S. divinorum from each of the following rather rare references, translating to English where necessary. The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. Amongst the Mazatecs, Salvia divinorum (Diviner's sage) is known under such names as ska Maria Pastora and Hierba Maria, which translate as "the herb of Mary" or "leaves of Mary the Shepherdess". In a recent paper, Jonathan 0tt has noted that the Mazatecs lack an indigenous name for Salvia divinorum, both the Christian theme of Mary, as well as sheep, having been introduced to Calea Zacatechichi Nemorosa the region during the Spanish conquest. The Mazatecs also list a method of consuming this plant that does not efficiently utilize its psychoactive content, and seem to be generally unaware of its tremendous potency. Based on this information, and the likelihood of its being a cultigen, Ott has suggested that Salvia divinorum may be a post-conquest introduction to the Sierra Mazateca. However, it has also been suggested, initially by R. Gordon Wasson, that Salvia divinorum may be the Aztec plant Pipiltzintzintli, an entheogen that was briefly described by a 17th century Spanish friar. Ott has found that the little information available regarding Pipiltzintzintli supports this hypothesis, while ruling out several other plants that have been suggested as candidates for this Aztec sacrament. Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation. R. Gordon Wasson, the famed ethnobotanist who introduced psilocybe mushrooms to western society, was also the first to personally describe an experience with Salvia divinorum. In July of 1961 he participated in a healing ceremony performed by a Mazatecan curandera. Wasson ingested the squeezed juice of 34 pairs of leaves, and described the results as "coming on sooner (than the mushrooms), being less sweeping, and lasting a shorter time. It did not go beyond the initial effects of the mushrooms - dancing colors in elaborate, three- dimensional designs." In 1962 Wasson was joined in Oaxaca by Swiss pharmacologist Albert Hofmann, inventor of LSD, who also first isolated psilocybin from mushrooms gathered in this same region. Hofmann brought an alcohol extract of Salvia divinorum back to Switzerland where he attempted to isolate the active component. He was unsuccessful, finding the extract to no longer be active, and suggested that the plant's active principal was unstable. Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation. Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and the psilocybin-containing mushrooms.
salvia d @ 3/16/2010 4:56:01 AM
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