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salvia divinorum extract Salvia perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are
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compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and Smoking Salvia Farinacea the psilocybin-containing mushrooms.
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R. Gordon Wasson, the famed ethnobotanist who introduced psilocybe mushrooms to western society, was also the first to personally describe an experience with Salvia divinorum. In July of 1961 he participated in a healing ceremony performed by a Mazatecan curandera. Wasson ingested the squeezed juice of 34 pairs of leaves, and described the results as "coming on sooner (than the mushrooms), being less sweeping, and lasting a shorter time. It did not go beyond the initial effects of the mushrooms - dancing colors in elaborate, three- dimensional designs." In 1962 Wasson was joined in Oaxaca by Swiss pharmacologist Albert Hofmann, inventor of LSD, who also first isolated psilocybin from mushrooms gathered in this same region. Hofmann brought an alcohol extract of Salvia divinorum back to Switzerland where he attempted to isolate the active component. He was unsuccessful, finding the extract to no longer be active, and suggested that the plant's active principal was unstable.
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Salvia farinacea Unless you believe that Salvia divinorum is the old Mexica (Aztec) narcotic plant pipiltzintzintli (I don’t), the story Diterpen of this fascinating mint began in the late 1930s. When R. Gordon Wasson and Albert Hoffman brought back material for Carl Epling to identify (Wasson 1962, 1963; Epling and Játiva-M 1962), they ended a search that had lasted nearly a quarter of
Salvia farinacea a century. Their party traveled through Oaxaca under the auspices of a famous Mexican anthropologist, Roberto Weitlaner (an Austrian by birth), who had been guiding expeditions to Oaxaca for
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The primary psychoactive constituent is trans-neoclerodane diterpenoid known as salvinorin A. Salvia also contains the closely related compounds salvinorins B-G, divinatorins A-E, salvinicins A and B, and hardwickiic acid. Salvinorin A is the most potent naturally-occurring hallucinogen known. It is active at doses as low as 100 µg 1]. Recent research has shown that salvinorin A is a remarkably potent and selective kappa opioid receptor agonist. It has been demonstrated that the effects of salvinorin A are blocked by kappa opioid receptor antagonists. This indicates that the effects of S. divinorum can be largely, if not entirely, attributed to kappa agonism. Salvinorin A is unique in that it is the only naturally occurring substance known to induce a visionary state via this mechanism of action. A discussion of the role of ska Maria Pastora in the native pharmacopeia is based Diviner S on previous reports and fieldwork by the authors, with a Mazatec shaman.
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* Y Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson Diterpen clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation.
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* Flavoured Herbal Molasses
* Happy Caps
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